WDFY2 and ARL6IP1

Data Source:
BioGRID (two hybrid)

		WDFY2	ARL6IP1
Description		WD repeat and FYVE domain containing 2	ADP ribosylation factor like GTPase 6 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Vesicle Intracellular Membrane-bounded Organelle	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Fat Cell Differentiation	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325)	Refractive error ( 32231278)
Interacting Genes		5 interacting genes: ARL6IP1 MTDH RPRM SYP YIF1A	77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		115825	23204
HPRD ID		18294	09641
Ensembl ID		ENSG00000139668	ENSG00000170540
Uniprot IDs		Q96P53	A0A024QYV7 Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?
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