ACOT7 and NCOA5

Data Source:
BioGRID (two hybrid)

		ACOT7	NCOA5
Description		acyl-CoA thioesterase 7	nuclear receptor coactivator 5
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Extracellular Exosome	Extracellular Space Nucleoplasm Actin Cytoskeleton
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Myristoyl-CoA Hydrolase Activity	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs			17alpha-Estriol
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Metabolite levels ( 31628463) QT interval ( 19305408)	Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)
Interacting Genes		24 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438	19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326
Entrez ID		11332	57727
HPRD ID		12517	14813
Ensembl ID		ENSG00000097021	ENSG00000124160
Uniprot IDs		O00154	Q9HCD5
PDB IDs		2QQ2	1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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