NCOA5 and KHDRBS2

Data Source:
BioGRID (two hybrid)

		NCOA5	KHDRBS2
Description		nuclear receptor coactivator 5	KH RNA binding domain containing, signal transduction associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Actin Cytoskeleton	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding	MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs		17alpha-Estriol
Diseases
GWAS		Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)
Interacting Genes		19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326	47 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPK HNRNPLL KHDRBS3 LINC01018 LMNTD2 LNX1 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM14 RBM3 RBMX RFC3 SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837
Entrez ID		57727	202559
HPRD ID		14813	13775
Ensembl ID		ENSG00000124160	ENSG00000112232
Uniprot IDs		Q9HCD5	A0A6Q8PGH5 Q5VWX1
PDB IDs		1V95 2J7X 2J7Y 4ZI1
Enriched GO Terms of Interacting Partners?
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