CHRM5 and CD82

Data Source:
BioGRID (two hybrid)

		CHRM5	CD82
Description		cholinergic receptor muscarinic 5	CD82 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity	Protein Binding
	Biological Process	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs		Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Malaria ( 31844061)	Blond vs. brown/black hair color ( 30531825) Cadmium levels ( 26025379) Hemostatic factors and hematological phenotypes ( 22443383) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Male-pattern baldness ( 27182965) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494) Plasma parathyroid hormone levels ( 30134803) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		31 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33	27 interacting genes: BDKRB2 CANX CD19 CD4 CD63 CHRM5 CREB3 EGFR ERBB2 ERBB3 FFAR2 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 KLRC1 LRP1 NUP88 PTGFRN SMIM3 VANGL1
Entrez ID		1133	3732
HPRD ID		00331	09004
Ensembl ID		ENSG00000184984	ENSG00000085117
Uniprot IDs		A0A024R9I2 P08912 Q8IVW0	P27701
PDB IDs		6OL9
Enriched GO Terms of Interacting Partners?
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