CHN1 and HEMK1

Data Source:
BioGRID (two hybrid)

		CHN1	HEMK1
Description		chimerin 1	HemK methyltransferase family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Mitochondrion
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding Ephrin Receptor Binding	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity
	Biological Process	Motor Neuron Axon Guidance Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction	DNA Methylation Protein Methylation
Pathways		Rho GTPase cycle
Drugs
Diseases		Duane retraction syndrome
GWAS		Post bronchodilator FEV1 ( 26634245)	Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)
Interacting Genes		16 interacting genes: ACVR1 ADORA2A ANKK1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 HTR6 MAPK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1	18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2
Entrez ID		1123	51409
HPRD ID		00319	13645
Ensembl ID		ENSG00000128656	ENSG00000114735
Uniprot IDs		P15882	A0A140VK98 B2RA37 Q9Y5R4
PDB IDs		2OSA 3CXL
Enriched GO Terms of Interacting Partners?
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