SUPT16H and NGDN

Data Source:
BioGRID (affinity chromatography technology)

		SUPT16H	NGDN
Description		SPT16 homolog, facilitates chromatin remodeling subunit	neuroguidin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm FACT Complex	Chromosome, Centromeric Region Nucleoplasm Nucleolus Mitochondrion Filopodium Axon Dendrite Small-subunit Processome
	Molecular Function	RNA Binding Protein Binding Nucleosome Binding	RNA Binding Protein Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Disassembly Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Viral Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter DNA Replication-independent Nucleosome Organization Regulation Of Signal Transduction By P53 Class Mediator	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Translation
Pathways		Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		13 interacting genes: CCT6A GTF2E2 H2AC13 H2AX H3-3A MCM3 MCM4 NEK9 PARP1 SREK1 SRPK2 SSRP1 SUMO2	5 interacting genes: AATF CSNK2B MFAP1 NOM1 SRPK2
Entrez ID		11198	25983
HPRD ID		16088	10708
Ensembl ID		ENSG00000092201	ENSG00000129460
Uniprot IDs		Q9Y5B9	Q8NEJ9
PDB IDs		4Z2M 4Z2N 5E5B 5UMT 5UMU 5XM2 6UPK 6UPL
Enriched GO Terms of Interacting Partners?
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