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TSG101 and MGRN1
Data Source:
BioGRID
(two hybrid, affinity chromatography technology, affinity chromatography technology)
TSG101
MGRN1
Description
tumor susceptibility 101
mahogunin ring finger 1
Image
No pdb structure
GO Annotations
Cellular Component
ESCRT I Complex
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Microtubule Organizing Center
Cytosol
Plasma Membrane
Endosome Membrane
Early Endosome Membrane
Late Endosome Membrane
Host Cell
Extracellular Exosome
Flemming Body
Nucleus
Cytoplasm
Early Endosome
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Coactivator Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Protein Monoubiquitination
Extracellular Transport
Cell Cycle Arrest
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Viral Budding
Cell Division
Intracellular Transport Of Virus
Autophagosome Maturation
Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Protein Monoubiquitination
Endosome To Lysosome Transport
Protein Ubiquitination
Negative Regulation Of CAMP-mediated Signaling
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Smoothened Signaling Pathway
Pathways
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Hemoglobin (
32888494
)
Milk allergy (maternal genetic effects) (
29489655
)
Triglyceride levels (
32154731
)
Interacting Genes
120 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
ARRDC1
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GMCL1
GOLM1
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
PDCD6IP
PDLIM7
PIAS1
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SNAPIN
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNIP1
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
ZWINT
13 interacting genes:
AMFR
TRIM74
TSG101
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2G2
UBE2I
UBE2J2
UBE2T
UBE2W
Entrez ID
7251
23295
HPRD ID
03229
07397
Ensembl ID
ENSG00000074319
ENSG00000102858
Uniprot IDs
Q99816
O60291
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6VME
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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