CD160 and RNF115

Data Source:
BioGRID (affinity chromatography technology)

		CD160	RNF115
Description		CD160 molecule	ring finger protein 115
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Plasma Membrane	Cytosol
	Molecular Function	Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Angiogenesis Adaptive Immune Response Mucosal Immune Response Positive Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Interferon-gamma Production Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process	Protein Polyubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653)	Apolipoprotein A1 levels ( 32203549) Breast cancer ( 25751625 29059683) HDL cholesterol levels ( 32203549) Platelet distribution width ( 32888494)
Interacting Genes		8 interacting genes: AGTRAP CMTM5 CMTM6 MAL2 MDM4 SYP THRA TNFRSF14	32 interacting genes: AKT1 APP ATN1 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2
Entrez ID		11126	27246
HPRD ID		06833	18328
Ensembl ID		ENSG00000117281	ENSG00000265491
Uniprot IDs		O95971 Q6FH89	Q9Y4L5
PDB IDs		6NG3 6NG9 6NGG
Enriched GO Terms of Interacting Partners?
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