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EMILIN1 and CDCA8
Data Source:
BioGRID
(two hybrid)
EMILIN1
CDCA8
Description
elastin microfibril interfacer 1
cell division cycle associated 8
Image
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Extracellular Space
Integrin Alpha4-beta1 Complex
Collagen-containing Extracellular Matrix
Extracellular Exosome
EMILIN Complex
Chromosome, Centromeric Region
Nucleoplasm
Nucleolus
Cytosol
Chromocenter
Midbody
Chromosome Passenger Complex
Protein-containing Complex
Intercellular Bridge
Spindle Midzone
Molecular Function
Extracellular Matrix Structural Constituent
Protein Binding
Extracellular Matrix Constituent Conferring Elasticity
Identical Protein Binding
Integrin Binding Involved In Cell-matrix Adhesion
Protein Binding
Biological Process
Aortic Valve Morphogenesis
Cell Adhesion
Cell-matrix Adhesion
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Cell Migration
Negative Regulation Of Angiogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of Collagen Biosynthetic Process
Elastic Fiber Assembly
Negative Regulation Of Cell Activation
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Macrophage Migration
Mitotic Sister Chromatid Segregation
Mitotic Metaphase Plate Congression
Chromosome Organization
Cell Division
Pathways
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA replication proteins
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Axial length (
24144296
)
Eyebrow thickness (
26926045
)
Interacting Genes
29 interacting genes:
ABI3
BEX3
BEX5
BFSP1
CDCA8
CENPQ
COG7
DYNC1I1
EMILIN2
FBXO28
GNG13
IFT20
LAIR2
LRRIQ1
MIA2
MTMR9
NECAB2
NMI
PLAC9
PRKAA2
RABGEF1
RIBC1
SNAPC5
TAB2
TAX1BP1
TSNAX
YJU2
ZC2HC1C
ZNF655
26 interacting genes:
AURKB
BIRC5
EMILIN1
FBXO17
GYS1
H3C14
HLA-DRB3
HMBOX1
INCENP
MAPKAPK5
NEK3
NKAPD1
NTAQ1
PIAS2
PIH1D2
RANBP2
RPRD1B
SENP3
SET
SGO1
SGO2
SNAPC5
SPANXN2
TTK
UBE2I
ZNF277
Entrez ID
11117
55143
HPRD ID
00563
13017
Ensembl ID
ENSG00000138080
ENSG00000134690
Uniprot IDs
Q9Y6C2
Q53HL2
PDB IDs
2KA3
2OII
2KDD
2QFA
2RAW
2RAX
6YIE
6YIF
6YIH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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