DNAJB4 and POLR1D

Data Source:
BioGRID (two hybrid)

		DNAJB4	POLR1D
Description		DnaJ heat shock protein family (Hsp40) member B4	RNA polymerase I and III subunit D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane	RNA Polymerase III Complex RNA Polymerase I Complex
	Molecular Function	ATPase Activator Activity Protein Binding Unfolded Protein Binding Chaperone Binding	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity
	Biological Process	Response To Unfolded Protein Response To Heat Positive Regulation Of ATPase Activity Chaperone Cofactor-dependent Protein Refolding	Transcription, DNA-templated
Pathways			Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases			Treacher Collins syndrome
GWAS		Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cutaneous melanoma or hair colour ( 32341527) Diastolic blood pressure ( 30224653) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Waist circumference ( 25673412)	Body mass index ( 26426971)
Interacting Genes		10 interacting genes: HSPA6 MDM2 OPRM1 PABPN1 POLR1D RUVBL2 SDIM1 SMAD3 TBL1X TBPL2	15 interacting genes: CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C POLR1G PXN
Entrez ID		11080	51082
HPRD ID		07486	17877
Ensembl ID		ENSG00000162616	ENSG00000186184
Uniprot IDs		B4DNN2 Q9UDY4	A0A087WTY1 P0DPB5 P0DPB6
PDB IDs
Enriched GO Terms of Interacting Partners?
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