HSF2BP and ANKRD55

  • Data Source:
  • BioGRID (two hybrid)

HSF2BP

ANKRD55
Description heat shock transcription factor 2 binding protein ankyrin repeat domain 55
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Celiac disease or Rheumatoid arthritis ( 21383967)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • IgA levels ( 28628107)
  • IgG glycosylation ( 23382691)
  • Immature fraction of reticulocytes ( 32888494)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Lung function (FEV1) ( 30061609)
  • Macular thickness ( 30535121)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 32888494)
  • Multiple sclerosis ( 31604244 24076602 27386562)
  • Optic disc size ( 31809533)
  • Pediatric autoimmune diseases ( 26301688)
  • Post-traumatic stress disorder ( 27167565)
  • Reticulocyte fraction of red cells ( 32888494)
  • Rheumatoid arthritis ( 30423114 30572963 23143596 24390342 20453842)
  • Rheumatoid arthritis (ACPA-negative) ( 23143596)
  • Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
  • Sero-negative rheumatoid arthritis ( 28706201)
  • Triglycerides ( 20686565)
  • Type 2 diabetes ( 27189021 22885922 26961502 29358691 30297969 26818947 32499647 30718926 28869590)
  • Urate levels ( 23263486)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 293 interacting genes: ABI2 ABLIM1 ACTN3 ADD1 ANAPC16 ANKRD55 ANKS1B ARHGAP45 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ATXN7L2 BARD1 BAX BAZ2B BCAS2 BEND7 BEX2 BLK BMI1 BYSL C10orf88 C18orf54 C1orf35 C1orf94 C2CD6 C4orf46 C5orf49 C7orf31 C9orf24 CAMSAP3 CARD9 CASS4 CBX8 CBY2 CCDC113 CCDC116 CCDC120 CCDC13 CCDC130 CCDC146 CCDC185 CCDC187 CCDC198 CCDC33 CCHCR1 CCSER1 CDC37 CDC73 CDCA7L CDR2L CDYL2 CEP55 CEP57 CKS1B CLIP4 CNNM1 CNNM3 CNOT2 COIL CTSZ CTTNBP2 CTTNBP2NL CWF19L2 DALRD3 DCDC2B DEFB112 DMAP1 DMRT3 DOCK8 DPF2 DUSP13 EAF1 EIF3D ELOA2 EMD ENKD1 EPHB3 EPM2AIP1 FAM107A FAM110A FAM110B FAM124B FAM161B FAM214B FAM228A FAM90A1 FBXO44 FHL2 FHL3 FLYWCH1 FUT9 GAS2L2 GAS8 GCM2 GEM GGN GNL3L GOLGA1 GPANK1 GPATCH2L GPBP1 GPKOW GPSM3 H2AW HASPIN HCK HDAC4 HEXIM2 HEY2 HNRNPH2 HOMEZ HOXB5 HOXC8 HSF2 IER2 IL16 INO80B INPP5J INSYN2A IPMK IQCC ITGB3BP JRK KANK2 KAT5 KIAA0408 KIF24 KIF5B KIF9 KIFC3 KLF4 L3MBTL2 L3MBTL3 L3MBTL4 LAGE3 LEP LGALS4 LMO4 LNX1 LRRC29 LRRC56 LRRN4 LUZP4 MAGED1 MAGOHB MARCHF7 MEF2A MFAP1 MISP MKRN3 MVB12A MYOZ3 NAB2 NCK2 NFIL3 NHSL2 NME4 NPPA NSMF NTAQ1 NUDT10 NXF1 ODF3B ODF3L2 OPTN P2RX7 PAK6 PAPSS2 PARD6B PDLIM7 PICK1 PKD2 PKN1 PKP1 PLB1 PLEKHA2 PLEKHA7 PNMA5 POGZ POLDIP3 POMC PPM1K PPP1R18 PPP1R32 PRPF18 PRPF3 PRPF31 PRR5L PSMA1 PSTPIP1 RAB11FIP2 RAB36 RAB3IL1 RAD51D RALY RBM17 RBM41 RBM48 RCOR3 REXO4 RIBC1 RIN1 RNF135 RNF169 ROBO3 RPS28 RTP5 SAMD4A SAPCD1 SART1 SAXO1 SCNM1 SDCBP SELENOV SEMA3B SEMA4C SEPTIN1 SEPTIN9 SETDB1 SH2D4A SHFL SHISA6 SIRPA SLAIN1 SLC6A1 SMARCB1 SMARCD1 SMG9 SNAPC1 SNW1 SNX18 SNX21 SPATA22 SPEG SPG7 SPRED1 SPRY1 SYCE1L SYNGAP1 TAB2 TAGAP TASOR2 TBC1D1 TBC1D30 TCEA2 TCF19 TEPSIN TFIP11 THAP6 TMEFF2 TMSB4X TNS4 TOX2 TP53BP2 TRAF5 TRARG1 TSEN15 TSGA10IP TSHZ3 TTC23 TTC9C TULP3 UBE2I UPF2 UPRT USP20 VEZF1 VHL VPS72 WASF1 WASHC1 WDR25 ZBTB16 ZBTB42 ZC2HC1C ZCWPW2 ZFC3H1 ZGPAT ZNF185 ZNF250 ZNF417 ZNF511 ZNF564 ZNF581 ZNF587 ZNF648 ZNF688 ZNF774 ZNF835 ZNF84 ZNF844 22 interacting genes: ABI2 ANKS1A BACH2 BANP BOLA2 BOLA2B CABP5 CFAP206 CLIC3 FHL2 FHL5 FRS3 HGS HSF2BP NCK2 NOXA1 PFDN5 PTK6 TEKT4 TRIM23 ZMYND19 ZSCAN1
Entrez ID 11077 79722
HPRD ID 05186 07758
Ensembl ID ENSG00000160207 ENSG00000164512
Uniprot IDs O75031 Q6IAT7 Q3KP44
PDB IDs
Enriched GO Terms of Interacting Partners?
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