COPS6 and PAEP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPS6	PAEP
Description		COP9 signalosome subunit 6	progestagen associated endometrial protein
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Metallopeptidase Activity Isopeptidase Activity	Protein Binding Small Molecule Binding
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair Viral Process Post-translational Protein Modification	Apoptotic Process Multicellular Organism Development Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Sperm Capacitation Regulation Of Binding Of Sperm To Zona Pellucida
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs			12-Bromododecanoic Acid Palmitic Acid Glycerin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		93 interacting genes: ANXA1 ANXA7 ASH2L BFSP2 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCBE1 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS7B COPS8 COPS9 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 LAMA4 LPL MAP3K1 MAP7D1 MAPK1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SHC3 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 USHBP1 VIM WIPI2 ZEB2 ZFHX3 ZNF24	22 interacting genes: A2M APP AQP6 AQP9 ARL13B COPS6 EEF1A1 ERVFRD-1 GORAB GPR42 GPX8 GRAMD2B HIBADH IFNLR1 IGSF21 LRIF1 PCDHGA4 PTPRC SMAD3 TMX2 UBE2E1 XRCC6
Entrez ID		10980	5047
HPRD ID		16735	01411
Ensembl ID		ENSG00000168090	ENSG00000122133
Uniprot IDs		Q7L5N1	A0A024R8D8 A6XNE0 B2R4F9 B4E3C0 P09466
PDB IDs		4D10 4D18 4QFT 4R14 4WSN 6R6H 6R7F 6R7H 6R7I	4R0B
Enriched GO Terms of Interacting Partners?
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