OS9 and PTH

Data Source:
BioGRID (affinity chromatography technology)

		OS9	PTH
Description		OS9 endoplasmic reticulum lectin	parathyroid hormone
Image
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Extracellular Region Extracellular Space
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding	Hormone Activity Protein Binding Parathyroid Hormone Receptor Binding Type 1 Parathyroid Hormone Receptor Binding Protein N-terminus Binding Receptor Ligand Activity Peptide Hormone Receptor Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Skeletal System Development Cellular Calcium Ion Homeostasis G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Rho Protein Signal Transduction Cell-cell Signaling Hormone-mediated Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Response To Lead Ion Regulation Of Gene Expression Negative Regulation Of Gene Expression Magnesium Ion Homeostasis Positive Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Response To Vitamin D Cellular Macromolecule Biosynthetic Process Response To Drug Bone Resorption Response To Ethanol Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II CAMP Metabolic Process Positive Regulation Of Glucose Import Response To Cadmium Ion Homeostasis Of Number Of Cells Within A Tissue Negative Regulation Of Calcium Ion Transport Phosphate Ion Homeostasis Positive Regulation Of Inositol Phosphate Biosynthetic Process Response To Parathyroid Hormone Response To Fibroblast Growth Factor Positive Regulation Of Cell Proliferation In Bone Marrow Negative Regulation Of Apoptotic Process In Bone Marrow Cell Positive Regulation Of Osteoclast Proliferation Negative Regulation Of Bone Mineralization Involved In Bone Maturation
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)	Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			D-norleucine ABX-PTH
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Bone mineral density ( 19874204) Childhood ear infection ( 27182965) Menarche (age at onset) ( 25231870) Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel ( 28935272)
Interacting Genes		19 interacting genes: ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FOXM1 HIF1A HSP90B1 LINC00839 MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B	6 interacting genes: ASPH BAG6 FEZ1 MEP1A PTH1R PTH2R
Entrez ID		10956	5741
HPRD ID		17804	01345
Ensembl ID		ENSG00000135506	ENSG00000152266
Uniprot IDs		Q13438	P01270
PDB IDs		3AIH	1BWX 1ET1 1ET2 1FVY 1HPH 1HPY 1HTH 1ZWA 1ZWB 1ZWD 1ZWE 1ZWF 1ZWG 2L1X 3C4M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?