OS9 and FOXM1

Data Source:
BioGRID (two hybrid)

		OS9	FOXM1
Description		OS9 endoplasmic reticulum lectin	forkhead box M1
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GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Positive Regulation Of Cell Population Proliferation Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Ras Protein Signal Transduction Regulation Of Cell Cycle Regulation Of Cell Cycle Arrest Negative Regulation Of Cell Aging Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Double-strand Break Repair
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)	Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Height ( 31562340)
Interacting Genes		19 interacting genes: ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FOXM1 HIF1A HSP90B1 LINC00839 MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B	18 interacting genes: BANP CCNE1 CDK1 CDK2 CDK4 CDK6 CHEK2 CREBBP DCAF1 OS9 OTUB1 SIRT1 STAT3 SUMO1 UBE2I UCHL3 USP21 ZBTB3
Entrez ID		10956	2305
HPRD ID		17804	03823
Ensembl ID		ENSG00000135506	ENSG00000111206
Uniprot IDs		Q13438	A0A0D9SFF0 A0A2P9DTZ1 A0A2P9DTZ8 A8K591 Q08050 Q53Y49
PDB IDs		3AIH	3G73
Enriched GO Terms of Interacting Partners?
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