OS9 and MEP1B

Data Source:
HPRD (two hybrid, in vitro)

		OS9	MEP1B
Description		OS9 endoplasmic reticulum lectin	meprin A subunit beta
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GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Extracellular Region Integral Component Of Plasma Membrane Meprin A Complex
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Proteolysis Inflammatory Response Toxin Transport
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Metabolite levels ( 23823483) TRAIL levels ( 27989323)
Interacting Genes		19 interacting genes: ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FOXM1 HIF1A HSP90B1 LINC00839 MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B	12 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT
Entrez ID		10956	4225
HPRD ID		17804	02667
Ensembl ID		ENSG00000135506	ENSG00000141434
Uniprot IDs		Q13438	J3QKX5 Q16820
PDB IDs		3AIH	4GWM 4GWN
Enriched GO Terms of Interacting Partners?
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