U2AF1 and SRRM4

Data Source:
BioGRID (two hybrid)

		U2AF1	SRRM4
Description		U2 small nuclear RNA auxiliary factor 1	serine/arginine repetitive matrix 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex	Nucleus
	Molecular Function	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	MRNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Blood and toenail selenium levels ( 25343990)	Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		51 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2	30 interacting genes: AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L2 LUZP4 MCRS1 RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SRRM1 SRSF11 TBC1D26 U2AF1 U2AF1L5 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1
Entrez ID		7307	84530
HPRD ID		01871	13897
Ensembl ID		ENSG00000160201	ENSG00000139767
Uniprot IDs		P0DN76 Q01081 Q7Z780	A7MD48 V5T9A0
PDB IDs		1JMT
Enriched GO Terms of Interacting Partners?
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