GJB6 and KLRC1

Data Source:
BioGRID (two hybrid)

		GJB6	KLRC1
Description		gap junction protein beta 6	killer cell lectin like receptor C1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Filament Gap Junction Connexin Complex Integral Component Of Membrane Apical Plasma Membrane Cell Junction	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Gap Junction Channel Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding
	Biological Process	Apoptotic Process Cell-cell Signaling Aging Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Cell Communication By Electrical Coupling Gap Junction Assembly Response To Lipopolysaccharide Maintenance Of Blood-brain Barrier Ear Morphogenesis Inner Ear Development Response To Electrical Stimulus Transmembrane Transport Cellular Response To Glucose Stimulus Gap Junction-mediated Intercellular Transport	Negative Regulation Of T Cell Mediated Cytotoxicity CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Natural Killer Cell Inhibitory Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		Gap junction assembly	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases		Ectodermal dysplasia, hidrotic; Clouston syndrome Deafness, autosomal recessive
GWAS		Facial emotion recognition (happy faces) ( 28608620)	Blood protein levels ( 28240269) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Reticulocyte count ( 32888494)
Interacting Genes		14 interacting genes: CHRM5 CNST EBP F2RL1 GJB2 GPR61 KLRC1 LHFPL5 MS4A13 SEC22A SEC22B SLC10A6 TMEM218 TMEM60	45 interacting genes: ATP6V0B ATP6V0C BMP10 BRICD5 C3orf52 CD151 CD82 CGRRF1 CLDN11 CLEC2D CLEC7A CLRN2 CTXN3 CXCL14 CYB561A3 EMP1 EMP3 ERMP1 GJB2 GJB4 GJB6 GPR61 HLA-E KLRD1 KLRG1 LSMEM2 MAL MALL MS4A13 NKG7 PLP1 PMP22 PTPN11 PTPN6 SFTPC TMEM182 TMEM262 TMEM54 TMPPE TSPO2 UNC93B1 UPK1B VAMP5 VTI1B ZFPL1
Entrez ID		10804	3821
HPRD ID		05107	01192
Ensembl ID		ENSG00000121742	ENSG00000134545
Uniprot IDs		A0A024RDS4 O95452	P26715
PDB IDs			2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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