GJB6 and GPR61

Data Source:
BioGRID (two hybrid)

		GJB6	GPR61
Description		gap junction protein beta 6	G protein-coupled receptor 61
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Filament Gap Junction Connexin Complex Integral Component Of Membrane Apical Plasma Membrane Cell Junction	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Gap Junction Channel Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process	Apoptotic Process Cell-cell Signaling Aging Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Cell Communication By Electrical Coupling Gap Junction Assembly Response To Lipopolysaccharide Maintenance Of Blood-brain Barrier Ear Morphogenesis Inner Ear Development Response To Electrical Stimulus Transmembrane Transport Cellular Response To Glucose Stimulus Gap Junction-mediated Intercellular Transport	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling
Pathways		Gap junction assembly
Drugs
Diseases		Ectodermal dysplasia, hidrotic; Clouston syndrome Deafness, autosomal recessive
GWAS		Facial emotion recognition (happy faces) ( 28608620)	Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		14 interacting genes: CHRM5 CNST EBP F2RL1 GJB2 GPR61 KLRC1 LHFPL5 MS4A13 SEC22A SEC22B SLC10A6 TMEM218 TMEM60	20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		10804	83873
HPRD ID		05107	06077
Ensembl ID		ENSG00000121742	ENSG00000156097
Uniprot IDs		A0A024RDS4 O95452	G4XH66 Q9BZJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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