TRAF3IP2 and STK16

Data Source:
BioGRID (two hybrid)

		TRAF3IP2	STK16
Description		TRAF3 interacting protein 2	serine/threonine kinase 16
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Protein Binding Ubiquitin Protein Ligase Activity	Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	B Cell Apoptotic Process Positive Regulation Of Defense Response To Virus By Host Inflammatory Response Humoral Immune Response Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K63-linked Ubiquitination Interleukin-17-mediated Signaling Pathway	Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998) Psoriasis ( 25903422 20953188 20953190 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624 20953186) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Ulcerative colitis ( 28067908)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		23 interacting genes: CD40 CHUK FHL3 GOLGA2 HSD17B10 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIM55 TRIM63 TRIP6 UBC UBE2V1	84 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774
Entrez ID		10758	8576
HPRD ID		06129	05281
Ensembl ID		ENSG00000056972	ENSG00000115661
Uniprot IDs		O43734	B4DPS1 B8ZZI5 O75716
PDB IDs			2BUJ
Enriched GO Terms of Interacting Partners?
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