SLC12A7 and TMEM54

Data Source:
BioGRID (two hybrid)

		SLC12A7	TMEM54
Description		solute carrier family 12 member 7	transmembrane protein 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Protein-containing Complex Synapse	Cellular_component Integral Component Of Membrane
	Molecular Function	Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding	Molecular_function Protein Binding
	Biological Process	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Biological_process
Pathways		Cation-coupled Chloride cotransporters
Drugs		Potassium chloride
Diseases
GWAS		Granulocyte count ( 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) JT interval ( 29874175) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 20139978 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Weight ( 28552196) White blood cell count ( 32888494)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		14 interacting genes: GJB1 GPR61 MS4A13 OPRD1 OTP SERINC2 SLC10A1 SLC10A6 SLC35C2 TMBIM6 TMEM147 TMEM237 TMEM54 YIPF6	24 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B
Entrez ID		10723	113452
HPRD ID		09221	12524
Ensembl ID		ENSG00000113504	ENSG00000121900
Uniprot IDs		Q9Y666	Q969K7
PDB IDs
Enriched GO Terms of Interacting Partners?
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