NOP56 and TCOF1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		NOP56	TCOF1
Description		NOP56 ribonucleoprotein	treacle ribosome biogenesis factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Membrane Box C/D RNP Complex Small-subunit Processome Pre-snoRNP Complex	Fibrillar Center Nucleoplasm Nucleolus Cytosol
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding Cadherin Binding Histone Methyltransferase Binding	RNA Binding Transporter Activity Protein Binding Protein-macromolecule Adaptor Activity Protein Heterodimerization Activity Scaffold Protein Binding
	Biological Process	RRNA Processing	Skeletal System Development Regulation Of Translation Neural Crest Formation Neural Crest Cell Development Nucleolar Large RRNA Transcription By RNA Polymerase I
Pathways		Association of TriC/CCT with target proteins during biosynthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)	Treacher Collins syndrome
GWAS			Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		8 interacting genes: BMPR2 CSNK2A1 DYNC1LI1 KLF6 PTEN SDCBP2 TCOF1 UBE2I	9 interacting genes: CSNK2A1 CSNK2A2 NOP56 PCNA SPOP SRPK2 TM9SF1 UBC UBTF
Entrez ID		10528	6949
HPRD ID		10119	06026
Ensembl ID		ENSG00000101361	ENSG00000070814
Uniprot IDs		O00567	B4DRA2 E7ETY2 H0Y8Y7 Q13428
PDB IDs
Enriched GO Terms of Interacting Partners?
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