NOP56 and SDCBP2

Data Source:
BioGRID (two hybrid)

		NOP56	SDCBP2
Description		NOP56 ribonucleoprotein	syndecan binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Membrane Box C/D RNP Complex Small-subunit Processome Pre-snoRNP Complex	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding Cadherin Binding Histone Methyltransferase Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	RRNA Processing	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		Association of TriC/CCT with target proteins during biosynthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: BMPR2 CSNK2A1 DYNC1LI1 KLF6 PTEN SDCBP2 TCOF1 UBE2I	65 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		10528	27111
HPRD ID		10119	18032
Ensembl ID		ENSG00000101361	ENSG00000125775
Uniprot IDs		O00567	Q9H190
PDB IDs
Enriched GO Terms of Interacting Partners?
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