Description |
nuclear receptor coactivator 2 |
tumor protein p53 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Diethylstilbestrol
- Genistein
- Metribolone
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- TO-901317
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 2-chloro-5-nitro-N-phenylbenzamide
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- Tributyltin
- 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol
- Estradiol acetate
- Estradiol benzoate
- Estradiol cypionate
- Estradiol dienanthate
- Estradiol valerate
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Diseases |
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GWAS |
- Apolipoprotein A1 levels ( 32203549)
- Cardiac Troponin-T levels ( 23247143)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- HDL cholesterol ( 30275531)
- HDL cholesterol levels ( 32203549 28334899)
- Intelligence (MTAG) ( 29326435)
- Metabolite levels ( 23823483)
- Metabolite levels (HVA-5-HIAA Factor score) ( 23319000)
- Multiple sclerosis ( 24076602)
- Non-small cell lung cancer ( 23144319)
- Plateletcrit ( 32888494)
- QT interval ( 24952745)
- Refractive error ( 32231278)
- Serum alkaline phosphatase levels ( 29403010)
- Spherical equivalent or myopia (age of diagnosis) ( 29808027)
- Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775)
- Systemic lupus erythematosus ( 33536424)
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Interacting Genes |
65 interacting genes:
ACTN2
AHR
ANKRD11
AR
ARNT
BRCA1
CARM1
CCND3
CCNT1
CDK4
CREBBP
CTNNB1
DDX17
DDX5
DLX2
DLX5
EID1
EP300
ESR1
ESR2
ESRRB
ETV1
FLII
FOS
GMEB1
H3-4
H4-16
HIF1A
HNF4A
JUN
KIF5A
KIF5B
KIF5C
MAGEA11
MEF2C
NKX2-1
NR1I2
NR2F1
NR3C1
NR4A1
OPN1LW
PIAS3
PML
PPARA
PPARD
PPARG
PPFIA1
PPFIA4
PRMT1
PSMB9
RARA
RORA
RXRA
SLC30A9
SMARCE1
SRCAP
STAT6
SUMO1
TAF9
THRA
THRB
TP53
TXNRD2
VDR
YWHAH
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489 interacting genes:
ABL1
ACKR3
ACTA1
AGT
AKAP5
AKT1
ANK2
ANKRD2
ANTKMT
ANXA2
ANXA3
APBB2
APEX1
APOH
APPL1
APTX
ARAF
ARID1A
ARID3A
ARIH2
ARL3
ARNT
ASH2L
ATF3
ATM
ATR
ATRX
ATXN3
AURKA
AXIN1
BAG5
BAG6
BAIAP2L1
BAK1
BANP
BARD1
BAX
BCCIP
BCL2
BCL2L1
BCL2L12
BCL2L2
BCL6
BCR
BLM
BMP1
BRCA1
BRCA2
BRF1
BTBD2
BTK
C10orf90
CABLES1
CABLES2
CAPG
CAPN1
CARM1
CBLC
CCDC106
CCL18
CCNA2
CCNG1
CCNH
CCT5
CD40LG
CDC14A
CDC14B
CDC25C
CDC34
CDC42
CDK1
CDK2
CDK4
CDK5
CDK6
CDK7
CDK8
CDK9
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CEBPZ
CENPX
CETP
CHD3
CHEK1
CHEK2
CHUK
COP1
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
COPS8
COX17
CR2
CRBN
CREBBP
CREBZF
CRK
CSNK1A1
CSNK1D
CSNK2A1
CSNK2A2
CSNK2B
CUL9
CXXC1
CYLD
DAPK3
DAXX
DCAF1
DDX20
DDX5
DGKZ
DHCR24
DHFR
DLEU1
DMTF1
DNAJB1
DNAJC7
DNMT3L
DTL
DVL2
E2F1
E4F1
EAF2
EEF2
EFEMP2
EGLN3
EGR1
EHMT1
EHMT2
EIF2AK2
EIF2S2
ELL
ELL3
EP300
EPHA2
EPHA3
ERBB2
ERCC2
ERCC3
ERCC6
ERH
ESR1
FBXO11
FBXO42
FBXW7
FCAMR
FGFR4
FOS
FOXO3
FXYD6
FZR1
GADD45A
GNL3
GPS1
GPS2
GPX2
GRWD1
GSK3B
GSTM4
GTF2H1
GTF2H4
GYS2
HABP4
HDAC1
HDAC2
HDAC3
HECTD3
HECW1
HEY1
HIF1A
HINFP
HIPK1
HIPK2
HMGA2
HMGB1
HMGB2
HNF4A
HNRNPUL1
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA9
HSPB1
HTT
HUWE1
IFI16
IKBKB
ING1
ING4
ING5
IRF7
ITPK1
JDP2
JUN
KAT2A
KAT2B
KAT5
KAT6A
KAT7
KAT8
KDM1A
KDM4D
KIAA0087
KLF4
KLF6
KMT5A
KPNA2
KPNA4
KPNB1
LACTB
LAMA4
LAMTOR5
LATS2
LDB3
MAD2L1BP
MAGEA2
MAGEB18
MAML1
MAP2K3
MAP2K5
MAP3K1
MAPK1
MAPK10
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MDC1
MDH1
MDM2
MDM4
MED1
MED17
MED21
MEN1
MET
MIF
MKRN2
MNAT1
MNDA
MPHOSPH6
MSL2
MSX1
MTA1
MTA2
MUC1
MUL1
MVP
MYBBP1A
MYC
NABP1
NABP2
NAP1L1
NAT10
NCL
NCOA1
NCOA2
NCOA3
NDN
NEDD8
NEIL3
NF2
NFKBIA
NFYA
NFYB
NGFR
NMT1
NMT2
NOP53
NPM1
NQO1
NR0B2
NR3C1
NR4A1
NTHL1
OTUB1
OTUD5
PADI1
PAFAH1B3
PARP1
PBK
PCDHA4
PDGFRA
PDLIM7
PELI1
PELI2
PELP1
PER2
PHB
PIAS1
PIAS2
PIAS4
PIN1
PLAGL1
PLCG2
PLK1
PLK3
PML
PNP
POLA1
PPA1
PPARGC1A
PPIB
PPM1D
PPP1CA
PPP1CC
PPP1R13L
PPP2CA
PPP2R2B
PPP4C
PRIM1
PRKAB2
PRKCA
PRKD1
PRKDC
PRKN
PRKRA
PRMT1
PRPF8
PSMB3
PSMC5
PSMD11
PSMD4
PSME3
PTEN
PTGS2
PTK2
PTTG1
RAB4A
RAB7A
RAD51
RANBP9
RAP1B
RB1
RBBP6
RBCK1
RBPJ
RCHY1
RELA
RING1
RNF125
RNF128
RNF38
RPA1
RPS6KA1
RPS6KA2
RPS6KA3
RRM2
RRM2B
RUNX3
S100A2
S100A4
S100A6
S100A8
S100B
SAT1
SCAMP1
SERPINB9
SETD7
SFN
SHISA5
SIN3A
SIN3B
SIRT1
SLC9A9
SMAD2
SMAD3
SMARCA4
SMARCB1
SMARCD1
SMN1
SMYD2
SNRPN
SP1
SP3
SRC
SRSF1
SSTR3
STAMBP
STARD10
STAT6
STK11
STK4
STX5
SUB1
SULT1E1
SUMO1
SYVN1
TADA3
TAF1
TAF1A
TAF1B
TAF1C
TAF9
TAF9B
TBP
TCF4
TEAD2
TEC
TEP1
TFAP2A
TFAP2C
TFDP1
TFIP11
THAP12
THAP8
THRB
TIAF1
TK1
TOP1
TOP1MT
TOP2A
TOP2B
TOPORS
TP53BP1
TP53BP2
TP53INP1
TP53RK
TP63
TP73
TRIAP1
TRIM27
TRIM39
TRIM67
TSC22D1
TSG101
TTK
TWIST1
TXN
UBB
UBE2A
UBE2D1
UBE2D3
UBE2I
UBE2K
UBE2L3
UBE2M
UBE2N
UBE2Q1
UBE2V2
UBE3A
UFD1
UHRF1
UHRF2
UIMC1
USP11
USP21
USP24
USP28
USP3
USP42
USP49
USP7
UTP14A
VRK1
WDR33
WDR5
WDR82
WRN
WT1
WWOX
XAF1
XPO1
XRCC6
YBX1
YWHAG
YWHAZ
YY1
YY2
ZBTB2
ZBTB49
ZCCHC10
ZHX1
ZIC3
ZMIZ2
ZNF148
ZNF24
ZNF302
ZNF679
ZNF839
ZNHIT1
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Entrez ID |
10499 |
7157 |
HPRD ID |
09066 |
01859 |
Ensembl ID |
ENSG00000140396
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ENSG00000141510
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Uniprot IDs |
B4DPW8
Q15596
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A0A087WT22
A0A087WXZ1
A0A087X1Q1
H2EHT1
K7PPA8
P04637
Q53GA5
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PDB IDs |
1GWQ
1GWR
1M2Z
1MV9
1MVC
1MZN
1P93
1T63
1T65
1UHL
1YOK
1ZDT
1ZDU
1ZKY
2AO6
2B1V
2B1Z
2B23
2FAI
2G44
2G5O
2LDC
2P15
2P1T
2P1U
2P1V
2Q7J
2Q7L
2YJD
2ZXZ
2ZY0
3A9E
3CLD
3DZU
3DZY
3E00
3E7C
3E94
3ERD
3FUG
3GN8
3K22
3K23
3KWY
3KYT
3L0E
3L0J
3L0L
3O1D
3O1E
3OAP
3OZJ
3PCU
3PLZ
3Q95
3R5M
3UP0
3UP3
4CSJ
4DOS
4E2J
4FHH
4FHI
4IA1
4IA2
4IA3
4IA7
4IQR
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4K4J
4K6I
4M8E
4M8H
4NIE
4NQA
4OC7
4P6W
4P6X
4PLD
4PLE
4POH
4POJ
4PP3
4PP5
4PP6
4PPP
4PPS
4PXM
4Q0A
4Q13
4QE6
4QE8
4RFW
4RMC
4RMD
4RME
4RUO
4UDC
4UDD
4WG0
4ZN7
4ZN9
4ZNH
4ZNS
4ZNT
4ZNU
4ZNV
4ZNW
4ZO1
4ZSH
5APH
5APJ
5DI7
5DID
5DIE
5DIG
5DK9
5DKB
5DKE
5DKG
5DKS
5DL4
5DLR
5DMC
5DMF
5DP0
5DRJ
5DRM
5DTV
5DU5
5DUE
5DUG
5DUH
5DVS
5DVV
5DWE
5DWG
5DWI
5DWJ
5DX3
5DXB
5DXE
5DXG
5DXK
5DXM
5DXP
5DXQ
5DXR
5DY8
5DYB
5DYD
5DZ0
5DZ1
5DZ3
5DZH
5DZI
5E0W
5E0X
5E14
5E15
5E19
5E1C
5EC9
5EGV
5EHJ
5EI1
5EIT
5G3J
5G42
5G43
5G44
5G45
5G46
5G5W
5H1E
5HYR
5I4V
5IAW
5ICK
5KCC
5KCD
5KCE
5KCF
5KCT
5KCU
5KCW
5KD9
5KR9
5KRA
5KRC
5KRF
5KRH
5KRI
5KRJ
5KRK
5KRL
5KRM
5KRO
5L11
5LGA
5LYQ
5MK4
5NFP
5NFT
5NI5
5NI7
5NI8
5NIB
5Q17
5SYZ
5T1Z
5TLD
5TLF
5TLG
5TLL
5TLM
5TLO
5TLP
5TLT
5TLU
5TLV
5TLX
5TLY
5TM1
5TM2
5TM3
5TM4
5TM5
5TM6
5TM7
5TM8
5TM9
5TML
5TMM
5TMO
5TMQ
5TMR
5TMS
5TMT
5TMU
5TMV
5TMW
5TMZ
5TN1
5TN3
5TN4
5TN5
5TN6
5TN7
5TN8
5U2D
5UAN
5VB3
5VB5
5VB6
5VB7
5VQK
5VQL
5WGQ
5WZX
5XPL
5Y1J
5Y49
5YP5
5YXB
5YXD
5YXJ
5YXL
5Z12
6CZN
6D0F
6EL6
6EL7
6EL9
6ESN
6KKB
6KKE
6KNU
6KNV
6KNW
6LIT
6OQX
6OQY
6OR1
6R7A
6R7J
6R7K
6SJM
6STI
6VIF
7A77
7A78
7A79
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1A1U
1AIE
1C26
1DT7
1GZH
1H26
1HS5
1JSP
1KZY
1MA3
1OLG
1OLH
1PES
1PET
1SAE
1SAF
1SAK
1SAL
1TSR
1TUP
1UOL
1XQH
1YC5
1YCQ
1YCR
1YCS
2AC0
2ADY
2AHI
2ATA
2B3G
2BIM
2BIN
2BIO
2BIP
2BIQ
2F1X
2FEJ
2FOJ
2FOO
2GS0
2H1L
2H2D
2H2F
2H4F
2H4H
2H4J
2H59
2J0Z
2J10
2J11
2J1W
2J1X
2J1Y
2J1Z
2J20
2J21
2K8F
2L14
2LY4
2MEJ
2MWO
2MWP
2MWY
2MZD
2OCJ
2PCX
2RUK
2VUK
2WGX
2X0U
2X0V
2X0W
2XWR
2YBG
2YDR
2Z5S
2Z5T
3D05
3D06
3D07
3D08
3D09
3D0A
3DAB
3DAC
3IGK
3IGL
3KMD
3KZ8
3LW1
3OQ5
3PDH
3Q01
3Q05
3Q06
3SAK
3TG5
3TS8
3ZME
4AGL
4AGM
4AGN
4AGO
4AGP
4AGQ
4BUZ
4BV2
4HFZ
4HJE
4IBQ
4IBS
4IBT
4IBU
4IBV
4IBW
4IBY
4IBZ
4IJT
4KVP
4LO9
4LOE
4LOF
4MZI
4MZR
4QO1
4RP6
4RP7
4X34
4XR8
4ZZJ
5A7B
5AB9
5ABA
5AOI
5AOJ
5AOK
5AOL
5AOM
5BUA
5ECG
5G4M
5G4N
5G4O
5HOU
5HP0
5HPD
5LAP
5LGY
5MCT
5MCU
5MCV
5MCW
5MF7
5MG7
5MHC
5MOC
5O1A
5O1B
5O1C
5O1D
5O1E
5O1F
5O1G
5O1H
5O1I
5OL0
5UN8
5XZC
6FF9
6FJ5
6GGA
6GGB
6GGC
6GGD
6GGE
6GGF
6R5L
6RJZ
6RK8
6RKI
6RKK
6RKM
6RL3
6RL4
6RL6
6RM5
6RM7
6RWH
6RWI
6RWS
6RWU
6RX2
6RZ3
6S39
6S3C
6S40
6S9Q
6SHZ
6SI0
6SI1
6SI2
6SI3
6SI4
6SIN
6SIO
6SIP
6SIQ
6SL6
6SLV
6T58
6V4F
6V4H
6VQO
6VR1
6VR5
6VRM
6VRN
7BWN
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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