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NXF1 and MID2
Data Source:
BioGRID
(two hybrid)
NXF1
MID2
Description
nuclear RNA export factor 1
midline 2
Image
GO Annotations
Cellular Component
Transcription Export Complex
Nucleus
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Nuclear Inclusion Body
Cytoplasm
Microtubule
Extracellular Exosome
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Transcription Coactivator Activity
Microtubule Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Homodimerization Activity
Phosphoprotein Binding
Biological Process
RNA Export From Nucleus
MRNA Export From Nucleus
Viral Process
Poly(A)+ MRNA Export From Nucleus
Positive Regulation Of Autophagy
Protein Ubiquitination
Negative Regulation Of Viral Transcription
Protein Localization To Microtubule
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Viral Release From Host Cell
Pathways
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
108 interacting genes:
ALYREF
AUNIP
BACH2
BECN1
BIN3
BIRC2
BLMH
BTBD18
C10orf55
C12orf40
CAMK2G
CCDC120
CCDC196
CCDC197
CCDC7
CDYL2
CLK2
CLK3
CSNK2A1
DHX9
DVL3
ECSIT
EIF4A3
ELAVL4
ESRRA
FAM9A
FTO
GFAP
GOLGA6L9
GPBP1
GTPBP2
HNRNPUL1
HOMEZ
HOXA1
HSF2BP
IMPA1
IPO11
IPO4
ISY1-RAB43
KATNBL1
KCTD5
KCTD7
KRT40
LCE3E
LDOC1
LUZP4
MAGOH
MAP1A
MAP1B
MBD3L1
MID2
MRNIP
MTUS2
NKAPD1
NME4
NUP153
NUP214
NUP62
NUP98
NXF2
NXF3
NXF5
NXT1
NXT2
PIH1D2
PPP1R12C
PRKAR1B
PRPH
PRR3
RAD51
RAE1
RAN
RANBP2
RBM15B
RBM8A
RPRD1A
SGTA
SH2D3A
SH3GLB2
SLAIN1
SNW1
SPATC1L
SRPK2
SRSF1
SRSF3
SRSF7
STRAP
SYCP3
TBC1D14
TCP10L
TEX9
THOC5
TIFA
TNFAIP1
TNPO1
TNPO2
TRA2A
TRA2B
U2AF1
UBQLN1
UBQLN4
UPF3A
VPS28
XIST
ZBED2
ZNF250
ZNF343
ZNF438
238 interacting genes:
ADAMTSL4
AEN
ALDH3B1
ANKS1A
AP1M1
AQP1
ARHGEF5
ATRIP
AXIN1
BAHD1
BCL6B
BLK
BLZF1
BRCA1
BRMS1L
BYSL
C1orf35
CALCOCO2
CARD9
CARHSP1
CBX8
CCDC120
CCDC185
CCDC187
CCDC33
CCDC42
CCHCR1
CDK18
CEP57L1
CFP
CHD2
CNNM3
COX5B
CPSF4
CRACR2A
CREBRF
CTSZ
DCX
DGCR6
DGCR6L
DMRT3
DYDC1
EFHC2
EGFL7
EIF1AD
ELOA
ENKD1
EPN2
ETNK2
FAM107A
FAM161A
FAM161B
FAM214A
FAM214B
FAM50B
FAM90A1
FARS2
FASTKD5
FBF1
FBXL18
FBXW5
FOXD4L3
FRMD6
FSD2
GAS2L2
GAS8
GCC1
GEM
GFI1B
GMCL1
GOLGA2
GOLGA7
GORASP2
GPANK1
GPKOW
GSC2
HAPLN2
HCK
HDAC4
HDX
HNRNPLL
HOXB2
HOXB5
HOXB9
IGBP1
IGFN1
IHO1
IKZF3
IL16
INO80B
IQCN
ISCU
ITGB4
JOSD1
KANK2
KIF1A
KIF9
KIFC3
KRT27
KRT31
KRT40
KRT75
KRT76
LAGE3
LENG1
LGALS14
LGALS8
LMNB2
LMNTD2
LMO3
LMO4
LNX1
LONRF1
LRRC45
LZTS1
LZTS2
MAGEA6
MAGOHB
MEOX1
MEOX2
METTL17
MFAP1
MID1
MID1IP1
MOS
MVP
NCOA4
NR1D2
NSMF
NXF1
OTUB2
PICK1
PKN1
POLDIP3
PPP1R18
PRDM16
PRPF3
PRPF31
PSMA1
PTCD2
PTPDC1
QARS1
RABGEF1
RANBP3L
RCOR3
REL
RLN1
RNF6
RORB
RPH3AL
RPP25L
RUNX1T1
RXRB
SCNM1
SDCBP
SEPTIN1
SHFL
SLC25A48
SLC25A6
SNAI1
SNAP47
SPAG5
SPATA24
SPG21
SPRY2
STX11
SYNGAP1
SYT17
TASOR2
TBC1D22B
TCAF1
TCEA2
TCEANC
TEKT1
THAP7
TMEM14B
TOP3B
TRIM27
TRIM29
TRIM32
TRIM41
TRIM42
TRIM54
TRIM69
TRPV6
TSGA10
TTC23
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2K
UBE2U
UBTD1
UNC45A
USP2
USP25
USP54
UTP23
UTP25
WT1-AS
ZBTB16
ZBTB24
ZBTB42
ZC2HC1C
ZFYVE21
ZGPAT
ZIM2
ZNF124
ZNF165
ZNF177
ZNF24
ZNF250
ZNF266
ZNF408
ZNF410
ZNF417
ZNF438
ZNF440
ZNF451
ZNF497
ZNF552
ZNF559-ZNF177
ZNF564
ZNF587
ZNF648
ZNF669
ZNF688
ZNF696
ZNF764
ZNF774
ZNF784
ZNF785
ZNF792
ZRANB1
ZSCAN12
Entrez ID
10482
11043
HPRD ID
04035
02191
Ensembl ID
ENSG00000162231
ENSG00000080561
Uniprot IDs
Q59E96
Q9UBU9
Q6GX22
Q9UJV3
PDB IDs
1FO1
1FT8
1GO5
1JKG
1JN5
1KOH
1KOO
1OAI
2Z5K
2Z5M
3RW6
3RW7
4WYK
6E5U
2DJA
2DMK
Enriched GO Terms of Interacting Partners
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