COG5 and COG4

Data Source:
HPRD (in vitro, in vivo)

		COG5	COG4
Description		component of oligomeric golgi complex 5	component of oligomeric golgi complex 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Golgi Apparatus Cytosol Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Inter-Golgi Cisterna Vesicle-mediated Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol levels ( 32203549) LDL cholesterol ( 30275531) Macular thickness ( 30535121) Medication use (beta blocking agents) ( 31015401) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Osteoarthritis ( 20112360) Pulse pressure ( 30224653 30578418) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		5 interacting genes: APC COG4 COG7 MEFV RAC1	15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9
Entrez ID		10466	25839
HPRD ID		08436	08444
Ensembl ID		ENSG00000164597	ENSG00000103051
Uniprot IDs		Q9UP83	A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3
PDB IDs			3HR0
Enriched GO Terms of Interacting Partners?
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