COG4 and SEPTIN2

Data Source:
BioGRID (two hybrid)

		COG4	SEPTIN2
Description		component of oligomeric golgi complex 4	septin 2
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GO Annotations	Cellular Component	Golgi Membrane Cytosol Golgi Transport Complex Trans-Golgi Network Membrane	Exocyst Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Golgi Vesicle Prefusion Complex Stabilization	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		15 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 FAM110A FARSA MTNR1B PSMA1 SEPTIN2 SORBS3 TXNDC9	21 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 CSNK2A1 DAZAP2 ESR1 JPT2 MTOR PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5
Entrez ID		25839	4735
HPRD ID		08444	03297
Ensembl ID		ENSG00000103051	ENSG00000168385
Uniprot IDs		A0A0A0MS45 J3KNI1 Q8N8L9 Q9H9E3	A0A384N6H6 Q15019
PDB IDs		3HR0	2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR
Enriched GO Terms of Interacting Partners?
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