BAIAP2 and BAIAP2L1

Data Source:
BioGRID (two hybrid)

		BAIAP2	BAIAP2L1
Description		BAR/IMD domain containing adaptor protein 2	BAR/IMD domain containing adaptor protein 2 like 1
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GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Actin Cytoskeleton Filopodium Extracellular Exosome	Nucleoplasm Cytosol Plasma Membrane Adherens Junction Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding Cytoskeletal Anchor Activity Identical Protein Binding Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion	Actin Binding Protein Binding Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Actin Filament Bundle Assembly Actin Crosslink Formation Cell-cell Adhesion Positive Regulation Of Actin Cytoskeleton Reorganization	Plasma Membrane Organization Response To Bacterium Positive Regulation Of Actin Filament Polymerization Regulation Of Insulin Receptor Signaling Pathway Actin Filament Bundle Assembly Actin Crosslink Formation Cell-cell Adhesion Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adverse response to drug ( 30420678) Beef consumption ( 32066663) Body size at age 10 ( 32376654) Breast cancer ( 29871690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling tense ( 29500382) General factor of neuroticism ( 30867560) Memory performance ( 24392092) Neurociticism ( 29500382) Neuroticism ( 29255261) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Pursuit maintenance gain ( 29064472) Sex hormone-binding globulin levels ( 22829776) White blood cell count ( 32888494)
Interacting Genes		39 interacting genes: ADGRB1 APP ATN1 BAIAP2L1 C19orf25 CDC42 COG6 DAPK1 DIAPH1 EGFR ENAH EPS8 ERG28 ESPN GRB10 HOXD8 KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3A2 SF3B4 SHANK1 SHANK2 SRPK2 TBX5 TP53BP2 WASF1 WASF2 YWHAG	10 interacting genes: BAG3 BAIAP2 CYSRT1 FASLG KHDRBS1 LANCL1 MDM2 TP53 WAS YWHAG
Entrez ID		10458	55971
HPRD ID		05686	11270
Ensembl ID		ENSG00000175866	ENSG00000006453
Uniprot IDs		I3L4C2 Q9UQB8	Q9UHR4
PDB IDs		1WDZ 1Y2O 2YKT 3RNJ 4JS0 6BCR 6BCY 6BD1 6BD2 6BQT 6ZEG 6ZEI	2KXC 2LNH
Enriched GO Terms of Interacting Partners?
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