ECI2 and TNPO3

Data Source:
BioGRID (two hybrid)

		ECI2	TNPO3
Description		enoyl-CoA delta isomerase 2	transportin 3
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GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane Intracellular Membrane-bounded Organelle	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Fatty-acyl-CoA Binding Dodecenoyl-CoA Delta-isomerase Activity Protein Binding	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Protein Import Into Nucleus
Pathways
Drugs		Myristic acid
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)
Interacting Genes		4 interacting genes: APP KDM1A PEX5 TNPO3	19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B
Entrez ID		10455	23534
HPRD ID		16269	18209
Ensembl ID		ENSG00000198721	ENSG00000064419
Uniprot IDs		A0A0C4DGA2 O75521	A0A024R794 B3KMX1 Q9Y5L0
PDB IDs		2CQU 2F6Q 4U18 4U19 4U1A	4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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