IFI30 and KRTAP4-12

Data Source:
BioGRID (two hybrid)

		IFI30	KRTAP4-12
Description		IFI30 lysosomal thiol reductase	keratin associated protein 4-12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Cytosol Cell Junction Lysosomal Lumen Intracellular Membrane-bounded Organelle	Keratin Filament
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Fibroblast Proliferation Protein Stabilization Interferon-gamma-mediated Signaling Pathway
Pathways		MHC class II antigen presentation Interferon gamma signaling
Drugs
Diseases
GWAS		Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244 24076602) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		3 interacting genes: KRTAP4-12 NOTCH2NLA TGM1	152 interacting genes: ADAM12 ADAMTSL4 ALPP AQP1 ATG12 ATN1 AXIN1 BAG4 BAHD1 BEX2 C10orf62 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CDX2 CHCHD3 CHIC2 CHRD CLCNKA CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 CYSRT1 DBF4B DLK2 EIF4E2 ELOA2 FAM107A FAM27E3 FAM76B FBXL18 FBXO34 FBXW5 FCHO1 FUCA2 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 IGSF8 ILF3 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP5-1 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NOTCH2NLA NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP POU4F2 PRKAB2 PRKAG1 PRR13 PTPMT1 QPRT R3HDM2 RERE RPS28 SHFL SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY1 SPRY2 TAP1 TBC1D16 TBC1D23 TGM1 THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF414 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF497 ZNF581 ZNF638 ZNF655 ZNF696 ZNF764 ZNF837 ZSCAN26
Entrez ID		10437	83755
HPRD ID		05234	13941
Ensembl ID		ENSG00000216490	ENSG00000213416
Uniprot IDs		A0A024R7N7 P13284	Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners?
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