SYCP2 and USP13

Data Source:
BioGRID (affinity chromatography technology)

		SYCP2	USP13
Description		synaptonemal complex protein 2	ubiquitin specific peptidase 13
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Lateral Element Nucleus	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Mitotic G1 Phase Synaptonemal Complex Assembly Male Meiotic Nuclear Division Female Meiotic Nuclear Division Fertilization Negative Regulation Of Apoptotic Process Male Genitalia Morphogenesis Cell Division Meiotic Nuclear Division	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Protein Phosphopantetheinylation Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Meiotic synapsis	Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS		Delirium ( 29631748)
Interacting Genes		3 interacting genes: HORMAD2 SRPK2 SYCP3	18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		10388	8975
HPRD ID		06822	04666
Ensembl ID		ENSG00000196074	ENSG00000058056
Uniprot IDs		Q9BX26	A0A0A6YZ17 Q92995
PDB IDs			2L80 2LBC
Enriched GO Terms of Interacting Partners?
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