BTN2A2 and GJB3

Data Source:
BioGRID (two hybrid)

		BTN2A2	GJB3
Description		butyrophilin subfamily 2 member A2	gap junction protein beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Cytoplasm Gap Junction Connexin Complex Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Signaling Receptor Binding Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway	In Utero Embryonic Development Placenta Development Cell-cell Signaling Spermatogenesis Skin Development Transmembrane Transport Cellular Response To Retinoic Acid
Pathways		Butyrophilin (BTN) family interactions	Gap junction assembly
Drugs
Diseases			Erythrokeratodermia variabilis Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Subcortical volume (MOSTest) ( 32665545)	Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2	15 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1
Entrez ID		10385	2707
HPRD ID		12545	04505
Ensembl ID		ENSG00000124508	ENSG00000188910
Uniprot IDs		A0A024R038 Q8WVV5	A0A654ICK0 O75712
PDB IDs
Enriched GO Terms of Interacting Partners?
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