GJB3 and TRARG1

Data Source:
BioGRID (two hybrid)

		GJB3	TRARG1
Description		gap junction protein beta 3	trafficking regulator of GLUT4 (SLC2A4) 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Gap Junction Connexin Complex Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle	Plasma Membrane Endomembrane System Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Gap Junction Channel Activity Protein Binding
	Biological Process	In Utero Embryonic Development Placenta Development Cell-cell Signaling Spermatogenesis Skin Development Transmembrane Transport Cellular Response To Retinoic Acid	Cellular Response To Insulin Stimulus Glucose Import In Response To Insulin Stimulus Protein Localization To Plasma Membrane Endosome To Plasma Membrane Protein Transport
Pathways		Gap junction assembly
Drugs
Diseases		Erythrokeratodermia variabilis Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		15 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1	101 interacting genes: APH1A APH1B AQP12B AQP2 ARL13B BCL2L13 BIK BSCL2 C6orf89 CCR4 CD300E CD53 CD79A CLDN12 CLDN7 CLDN8 CLEC10A CXCR1 CXCR2 DAGLA EBP EFNA4 ELOVL4 ERGIC3 FNDC9 FUT3 GJB3 GPR151 GPR42 GPR61 GPRC5D HSF2BP IFNGR2 IL3RA IRF1-AS1 KASH5 KCNC1 KRT34 KRTAP5-9 LAPTM4B LHFPL5 LY6E MEOX2 MFF MFSD14B MRM1 MRPS18B MTIF3 NPFFR2 NPY2R ODF4 OPN1LW OPRM1 OR7D4 OSTC PDZK1IP1 PLEKHB2 PSCA RHBDL1 RHCG RTP4 SCN3B SDCBP SGPL1 SLC10A1 SLC13A4 SLC14A2 SLC16A2 SLC1A5 SLC30A2 SLC34A2 SLC35F1 SLC36A1 SLC38A1 SLC38A11 SLC38A6 SLC39A1 SLC7A1 SLC7A14 SLCO3A1 SPAG4 SSMEM1 SYNPR TAAR9 TM4SF18 TMC4 TMEM179B TMEM237 TMEM248 TMEM31 TMEM45A TMEM52B TMEM69 TMEM71 TMEM80 TMEM9 TMPPE TTYH2 WFS1 YIPF6 ZDHHC4
Entrez ID		2707	286753
HPRD ID		04505	18248
Ensembl ID		ENSG00000188910	ENSG00000184811
Uniprot IDs		A0A654ICK0 O75712	Q8IXB3
PDB IDs
Enriched GO Terms of Interacting Partners?
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