APBB3 and APLP2

Data Source:
HPRD (in vitro)

		APBB3	APLP2
Description		amyloid beta precursor protein binding family B member 3	amyloid beta precursor like protein 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Actin Cytoskeleton Membrane	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane Extracellular Exosome
	Molecular Function	Amyloid-beta Binding Protein Binding Transcription Factor Binding Low-density Lipoprotein Particle Receptor Binding	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion	Platelet Degranulation G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Serum immune biomarker levels ( 32066700)	Blood protein levels ( 30072576)
Interacting Genes		6 interacting genes: APLP2 APP EGFR ERBB2 PDPK1 RAB4A	23 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 VKORC1 ZNF512B
Entrez ID		10307	334
HPRD ID		04089	00103
Ensembl ID		ENSG00000113108	ENSG00000084234
Uniprot IDs		O95704 Q59EH2 Q96DX9	A0A140VJE9 B4E3I5 Q06481
PDB IDs		2DYQ 2YSC	5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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