DCAF7 and DYRK1B

Data Source:
HPRD (in vitro)

		DCAF7	DYRK1B
Description		DDB1 and CUL4 associated factor 7	dual specificity tyrosine phosphorylation regulated kinase 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Multicellular Organism Development Protein Ubiquitination Post-translational Protein Modification	Protein Phosphorylation Myoblast Fusion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Adipose Tissue Development
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs			Fostamatinib
Diseases
GWAS			Macular thickness ( 30535121)
Interacting Genes		7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG	12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP
Entrez ID		10238	9149
HPRD ID		09340	05188
Ensembl ID		ENSG00000136485	ENSG00000105204
Uniprot IDs		P61962	A0A024R0I0 A0A024R0J6 A0A024R0M8 Q9Y463
PDB IDs
Enriched GO Terms of Interacting Partners?
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