DCAF7 and TLK2

Data Source:
BioGRID (affinity chromatography technology)

		DCAF7	TLK2
Description		DDB1 and CUL4 associated factor 7	tousled like kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Multicellular Organism Development Protein Ubiquitination Post-translational Protein Modification	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation
Drugs			Fostamatinib
Diseases
GWAS			Heel bone mineral density ( 30598549) Lifespan ( 25918517)
Interacting Genes		7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG	17 interacting genes: ASF1A ASF1B AURKA CEP70 DMAP1 FEZ1 FEZ2 FRMD6 GMCL1 IRF4 IRF7 MBP PAX5 PAX6 TLK1 UBE2I YWHAZ
Entrez ID		10238	11011
HPRD ID		09340	10527
Ensembl ID		ENSG00000136485	ENSG00000146872
Uniprot IDs		P61962	B4DUC2 J3QLK5 Q86UE8
PDB IDs			5O0Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?