DCAF7 and CBX1

Data Source:
BioGRID (affinity chromatography technology)

		DCAF7	CBX1
Description		DDB1 and CUL4 associated factor 7	chromobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Body Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Multicellular Organism Development Protein Ubiquitination Post-translational Protein Modification	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation	HCMV Early Events
Drugs
Diseases
GWAS			Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG	36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID		10238	10951
HPRD ID		09340	05149
Ensembl ID		ENSG00000136485	ENSG00000108468
Uniprot IDs		P61962	P83916 Q6IBN6
PDB IDs			2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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