Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TOPORS and UBE2D4
Data Source:
BioGRID
(two hybrid)
TOPORS
UBE2D4
Description
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
ubiquitin conjugating enzyme E2 D4 (putative)
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Spindle Pole
Gamma-tubulin Complex
Nucleus
Nucleoplasm
Centriole
Cytoplasmic Dynein Complex
PML Body
Nuclear Speck
Midbody
Photoreceptor Connecting Cilium
Ciliary Basal Body
Ubiquitin Ligase Complex
Nucleus
Molecular Function
DNA Binding
Antigen Binding
Ubiquitin-protein Transferase Activity
Protein Binding
SUMO Transferase Activity
DNA Topoisomerase Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Transcription, DNA-templated
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Retina Layer Formation
Protein Sumoylation
Protein Localization To Nucleus
Photoreceptor Cell Outer Segment Organization
Regulation Of Cell Population Proliferation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Transcription, DNA-templated
Retinal Rod Cell Development
Retinal Cone Cell Development
Positive Regulation Of Ubiquitin-protein Transferase Activity
Maintenance Of Protein Location In Nucleus
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of immune response proteins
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Retinitis pigmentosa (RP)
GWAS
Early spontaneous preterm birth (
31194736
)
Immune response to smallpox vaccine (IL-6) (
22610502
)
Metabolite levels (
23823483
)
Interacting Genes
28 interacting genes:
CASP8
CREBBP
EPM2A
H2AX
HABP4
MTDH
NKX3-1
SATB1
SERBP1
SIN3A
SNIP1
SPOP
SUMO1
SUMO2
TOP1
TP53
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2I
UBE2J1
UBE2L6
UBE2N
UBE2W
XRCC1
109 interacting genes:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
H3C1
H4C1
IKBKG
INCA1
ITCH
LNX1
LRSAM1
MAGEA11
MAP3K1
MARCHF3
MDM2
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
POLR2E
PRKN
RBCK1
RCHY1
REL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF216
RNF26
RNF31
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
STUB1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM62
TRIM8
UBA1
UBC
UBE4A
UBOX5
UBTD1
UBTD2
UFM1
UHRF2
UVSSA
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
10210
51619
HPRD ID
11642
14242
Ensembl ID
ENSG00000197579
ENSG00000078967
Uniprot IDs
Q9NS56
A0A024RA90
Q9UQL0
Q9Y2X8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?