CDK6 and TPX2

  • Data Source:
  • BioGRID (enzymatic study)

CDK6

TPX2

Description cyclin dependent kinase 6 TPX2 microtubule nucleation factor
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Immature fraction of reticulocytes ( 32888494)
  • Mean reticulocyte volume ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Prudent dietary pattern ( 28644415)
Interacting Genes 136 interacting genes: ABI2 AKT1 ANKRD12 APOBEC1 AR ARAF ARNT ATF6B ATXN1 BCL11A BECN1 CASC3 CBLC CBY1 CCND1 CCND2 CCND3 CCNE1 CCNH CCNI CD44 CDC37 CDC6 CDK4 CDK7 CDKN1A CDKN2A CDKN2B CDKN2C CDKN2D CLASRP CNOT7 CTNNB1 DDIT3 DEDD2 EBF4 EIF4ENIF1 ELK1 ELOA2 EPHA2 ERBB2 EZH2 FGFR4 FOXM1 FOXO3 FZR1 GLIS1 GLIS2 GRM1 H1-1 HGF HIF1A HSF1 ISL1 KAT2A KDELR2 KEAP1 KIF26B KLF10 LATS2 LPIN1 MAP2K3 MAP2K5 MAP3K5 MAPK14 MCM10 MCM2 MEF2D MET MLLT3 MSL3 MYC MZF1 N4BP1 NF2 NFATC3 NIPBL NUMA1 OTP PCNA PDGFRA PML POGZ PPARGC1A PPHLN1 PPM1B PPP2CA PRX PSMA3 RAF1 RASSF1 RB1 RBL1 RBL2 RBM23 RBPMS RUNX1 SENP3 SIRT1 SLBP SNIP1 SORBS1 SOX10 SOX5 SRSF1 SRSF11 SRSF12 SRSF2 SRSF7 SSBP2 STK11 SUMO1 SYNPO2 TEAD2 TERT TFDP1 TGFBR1 TJP2 TNFRSF1A TP53 TPX2 TRA2A TRA2B TRAK1 TRIM15 TSC1 UHRF2 USP17L2 VGLL4 ZEB1 ZFP36 ZMYM3 ZNF101 ZNF174 ZNF335 ZSCAN1 8 interacting genes: AURKA CDK6 GOLGA2 HMMR NAP1L1 SIAH2 SUMO2 THAP11
Entrez ID 1021 22974
HPRD ID 04533 05802
Ensembl ID ENSG00000105810 ENSG00000088325
Uniprot IDs Q00534 Q643R0 Q9ULW0
PDB IDs 1BI7 1BI8 1BLX 1G3N 1JOW 1XO2 2EUF 2F2C 3NUP 3NUX 4AUA 4EZ5 4TTH 5L2I 5L2S 5L2T 6OQL 6OQO 1OL5 3E5A 3HA6 4C3P 5LXM 6BJC 6VPG 6VPH 6VPI 6VPJ 6VPL 6VPM 6XKA
Enriched GO Terms of Interacting Partners?
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