ADAM10 and MAP3K8

  • Data Source:
  • BioGRID (two hybrid)

ADAM10

MAP3K8

Description ADAM metallopeptidase domain 10 mitogen-activated protein kinase kinase kinase 8
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Apolipoprotein A1 levels ( 32203549)
  • Chronotype ( 30696823)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Family history of Alzheimer's disease ( 30617256)
  • Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355)
  • Metabolite levels ( 23823483)
  • Schizophrenia ( 30285260)
Interacting Genes 7 interacting genes: AXL DLL1 EFNA1 EFNA2 EPHA3 SH3D19 TGFA 17 interacting genes: ACY3 AKT1 BMPR2 CD40 CHUK MAP2K1 MAP2K4 MAP3K14 NFKB1 NFKB2 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6
Entrez ID 102 1326
HPRD ID 03723 01863
Ensembl ID ENSG00000137845 ENSG00000107968
Uniprot IDs A0A024R5U5 O14672 P41279 Q6FG25
PDB IDs 1M1I 6BDZ 6BE6 4Y83 4Y85 5IU2
Enriched GO Terms of Interacting Partners?
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