LPAR6 and RPRM

Data Source:
BioGRID (two hybrid)

		LPAR6	RPRM
Description		lysophosphatidic acid receptor 6	reprimo, TP53 dependent G2 arrest mediator homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lysophosphatidic Acid Receptor Activity	Protein Binding
	Biological Process	Blastocyst Hatching G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway	Cell Cycle Arrest Regulation Of Mitotic Cell Cycle
Pathways		G alpha (q) signalling events P2Y receptors
Drugs		Promethazine
Diseases		Woolly hair, including: Autosomal-dominant woolly hair (ADWH); Autosomal-recessive woolly hair (ARWH); Autosomal-recessive woolly hair with or without hypotrichosis Localized autosomal recessive hypotrichosis
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730)
Interacting Genes		4 interacting genes: EMP1 RPRM SEC22A SMIM3	79 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22
Entrez ID		10161	56475
HPRD ID		16465	18002
Ensembl ID		ENSG00000139679	ENSG00000177519
Uniprot IDs		A0A024RDT2 B3KVQ5 P43657	Q9NS64
PDB IDs
Enriched GO Terms of Interacting Partners?
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