LPAR6 and SMIM3

Data Source:
BioGRID (two hybrid)

		LPAR6	SMIM3
Description		lysophosphatidic acid receptor 6	small integral membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lysophosphatidic Acid Receptor Activity	Protein Binding Identical Protein Binding
	Biological Process	Blastocyst Hatching G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways		G alpha (q) signalling events P2Y receptors
Drugs		Promethazine
Diseases		Woolly hair, including: Autosomal-dominant woolly hair (ADWH); Autosomal-recessive woolly hair (ARWH); Autosomal-recessive woolly hair with or without hypotrichosis Localized autosomal recessive hypotrichosis
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)
Interacting Genes		4 interacting genes: EMP1 RPRM SEC22A SMIM3	52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1
Entrez ID		10161	85027
HPRD ID		16465	12212
Ensembl ID		ENSG00000139679	ENSG00000256235
Uniprot IDs		A0A024RDT2 B3KVQ5 P43657	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?
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