AASS and PTPRZ1

Data Source:
BioGRID (affinity chromatography technology)

		AASS	PTPRZ1
Description		aminoadipate-semialdehyde synthase	protein tyrosine phosphatase receptor type Z1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Transcription Corepressor Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid Negative Regulation Of Histone Methylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine	Protein Dephosphorylation Central Nervous System Development Learning Or Memory Cytokine-mediated Signaling Pathway Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways		Lysine catabolism	Other interleukin signaling
Drugs		Glutamic acid NADH NADPH L-Saccharopine
Diseases		Hyperlysinemia
GWAS			Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)
Interacting Genes			13 interacting genes: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B PTN PTPRF TNR
Entrez ID		10157	5803
HPRD ID		05489	01481
Ensembl ID		ENSG00000008311	ENSG00000106278
Uniprot IDs		A4D0W4 Q9UDR5	B4DFE7 P23471
PDB IDs		5L76 5L78 5O1N 5O1O 5O1P	3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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