PTPRZ1 and ADD2

Data Source:
HPRD (in vivo)

		PTPRZ1	ADD2
Description		protein tyrosine phosphatase receptor type Z1	adducin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane	Cytosol Cytoskeleton Plasma Membrane F-actin Capping Protein Complex Postsynaptic Density Cytoplasmic Vesicle Plasma Membrane Raft
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Calmodulin Binding Protein Kinase Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Protein Dephosphorylation Central Nervous System Development Learning Or Memory Cytokine-mediated Signaling Pathway Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation	Synapse Assembly Actin Cytoskeleton Organization Hemopoiesis Positive Regulation Of Protein Binding Leukocyte Migration Leukocyte Tethering Or Rolling Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Protein-containing Complex Assembly
Pathways		Other interleukin signaling	Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)	Acne (severe) ( 24927181)
Interacting Genes		13 interacting genes: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B PTN PTPRF TNR	8 interacting genes: ADD1 APP CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A
Entrez ID		5803	119
HPRD ID		01481	00037
Ensembl ID		ENSG00000106278	ENSG00000075340
Uniprot IDs		B4DFE7 P23471	P35612 Q05DK5
PDB IDs		3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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