FXYD6-FXYD2 and BEST1

Data Source:
BioGRID (two hybrid)

		FXYD6-FXYD2	BEST1
Description		FXYD6-FXYD2 readthrough	bestrophin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Chloride Channel Complex
	Molecular Function		Chloride Channel Activity Identical Protein Binding
	Biological Process		Chloride Transport Visual Perception Transepithelial Chloride Transport Ion Transmembrane Transport Detection Of Light Stimulus Involved In Visual Perception Regulation Of Calcium Ion Transport Chloride Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases			Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC) Retinitis pigmentosa (RP)
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321)	Estradiol levels ( 22675492) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335)
Interacting Genes		33 interacting genes: APH1B APOL3 AQP6 AVPR2 BEST1 BNIP3 CERS4 CLDN5 FAM210B GPR152 GPR37L1 GPRC5D MTIF3 PGRMC2 RNF170 SLC10A1 SLC10A6 SLC16A13 SLC19A3 SLC2A13 SLC34A2 SLC35C2 SLC7A8 SPCS1 TLCD4 TMEM14B TMEM167B TMEM205 TMEM41A TMPPE TMX2 TRHR UNC93A	4 interacting genes: FXYD6-FXYD2 MS4A13 PPP2CA PPP2R5A
Entrez ID		100533181	7439
HPRD ID			01094
Ensembl ID		ENSG00000255245	ENSG00000167995
Uniprot IDs		A0A087WZ82 A0A0A6YYL5	A0A0S2Z4M4 A0A0S2Z579 B7Z1N8 B7Z375 O76090
PDB IDs
Enriched GO Terms of Interacting Partners?
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