BEST1

Description		bestrophin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Chloride Channel Complex
	Molecular Function	Chloride Channel Activity Identical Protein Binding
	Biological Process	Chloride Transport Visual Perception Transepithelial Chloride Transport Ion Transmembrane Transport Detection Of Light Stimulus Involved In Visual Perception Regulation Of Calcium Ion Transport Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases		Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC) Retinitis pigmentosa (RP)
GWAS		Estradiol levels ( 22675492) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335)
Interacting Genes		4 interacting genes: FXYD6-FXYD2 MS4A13 PPP2CA PPP2R5A
Entrez ID		7439
HPRD ID		01094
Ensembl ID		ENSG00000167995
Uniprot IDs		A0A0S2Z4M4 A0A0S2Z579 B7Z1N8 B7Z375 O76090
PDB IDs
Enriched GO Terms of Interacting Partners?
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