PIGK and ALPP

Data Source:
HPRD (in vitro, in vivo)

		PIGK	ALPP
Description		phosphatidylinositol glycan anchor biosynthesis class K	alkaline phosphatase, placental
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Protein Disulfide Isomerase Activity GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding	Magnesium Ion Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding
	Biological Process	Proteolysis Attachment Of GPI Anchor To Protein Protein Phosphopantetheinylation Protein Localization To Cell Surface	Dephosphorylation
Pathways		Attachment of GPI anchor to uPAR	Intra-Golgi traffic
Drugs			Calcium METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER
Diseases
GWAS		Chronotype ( 30696823 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Type 2 diabetes (age of onset) ( 28060188)	Blood protein levels ( 30072576) Height ( 19570815) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: ALPP GPAA1 PIGT	42 interacting genes: ADAMTSL4 ALPG CRCT1 CREB5 CXCL5 CYSRT1 FBXO34 GEMIN4 GPLD1 GSC2 HOXA1 IGFBP6 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP5-9 LATS1 LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE5A LELP1 MEOX2 NBPF19 NLGN3 NOTCH2NLA NR4A3 OTX1 PIGK POU4F2 RGS19 RGS20 SMCP TGM1
Entrez ID		10026	250
HPRD ID		05474	01379
Ensembl ID		ENSG00000142892	ENSG00000163283
Uniprot IDs		Q92643	B2R7C7 P05187
PDB IDs			1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?
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