TEN1 and STN1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TEN1	STN1
Description		TEN1 subunit of CST complex	STN1 subunit of CST complex
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm CST Complex	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton CST Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding Telomerase Inhibitor Activity Telomeric DNA Binding	Single-stranded DNA Binding Protein Binding Telomeric DNA Binding Single-stranded Telomeric DNA Binding
	Biological Process	Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Replication
Pathways		Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation	Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS		L-selectin levels ( 25576479)	Chronic obstructive pulmonary disease ( 30804561) Leukocyte telomere length ( 32109421) Uterine fibroids ( 31488892 30194396) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		1 interacting genes: STN1	19 interacting genes: APP C14orf119 C1orf109 CDK3 GOLGA2 LDLRAP1 LRRK2 MFHAS1 MKRN3 MVP NTAQ1 RCOR3 TEN1 TOLLIP TPP1 TRIML2 TUBGCP4 TXN2 ZDHHC17
Entrez ID		100134934	79991
HPRD ID		19459	14872
Ensembl ID		ENSG00000257949	ENSG00000107960
Uniprot IDs		Q86WV5	Q9H668
PDB IDs		4JOI 6W6W	4JOI 4JQF 6W6W
Enriched GO Terms of Interacting Partners?
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