STN1 and C14orf119

Data Source:
BioGRID (two hybrid)

		STN1	C14orf119
Description		STN1 subunit of CST complex	chromosome 14 open reading frame 119
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton CST Complex	Mitochondrion Cytosol
	Molecular Function	Single-stranded DNA Binding Protein Binding Telomeric DNA Binding Single-stranded Telomeric DNA Binding	Protein Binding
	Biological Process	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Replication
Pathways		Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Leukocyte telomere length ( 32109421) Uterine fibroids ( 31488892 30194396) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		19 interacting genes: APP C14orf119 C1orf109 CDK3 GOLGA2 LDLRAP1 LRRK2 MFHAS1 MKRN3 MVP NTAQ1 RCOR3 TEN1 TOLLIP TPP1 TRIML2 TUBGCP4 TXN2 ZDHHC17	57 interacting genes: ACTN1 ACTN4 ARID3C ARID5A AUNIP BEND7 BIN3 C1QTNF1 CCND3 CDC14A CHMP1A CLPP CTAG1A CTAG1B DDIT4L DECR2 DYNLL1 DYNLL2 HES6 HLX HMG20B ITGB3BP KHDC4 KRT4 KRT78 KRTAP13-3 LASP1 LDB2 LENG1 LRRCC1 MEOX1 MORN3 MYF5 NIF3L1 NME4 NRIP3 NUP54 NUP62 PBX4 PHACTR1 PINX1 RAB3IL1 REL RHOU RND3 RNF4 RPIA SMCP SNX8 SSX4 SSX4B STN1 SYCP3 TEX35 TLE5 UBXN11 WASHC1
Entrez ID		79991	55017
HPRD ID		14872	16595
Ensembl ID		ENSG00000107960	ENSG00000179933
Uniprot IDs		Q9H668	Q9NWQ9
PDB IDs		4JOI 4JQF 6W6W
Enriched GO Terms of Interacting Partners?
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