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TMEM262 and EDA2R
Data Source:
BioGRID
(two hybrid)
TMEM262
EDA2R
Description
transmembrane protein 262
ectodysplasin A2 receptor
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Signaling Receptor Activity
Biological Process
Multicellular Organism Development
Epidermis Development
Ectodermal Cell Differentiation
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
TNFs bind their physiological receptors
Drugs
Diseases
GWAS
Serum uric acid levels (
32514006
)
Balding (
26926045
)
Male-pattern baldness (
27182965
22032556
28196072
)
Interacting Genes
13 interacting genes:
AQP6
CD3G
CD79A
EDA2R
EMP1
FFAR2
GPR42
KLRC1
MANBAL
PSCA
SHISAL1
SLC10A6
UPK1B
16 interacting genes:
AGR3
ATP6V0C
C1QB
CASP8
CEBPE
EDA
FADD
GIMAP5
JAGN1
NKG7
PLP1
SGTA
STRIT1
TMEM262
TRAF3
TRAF6
Entrez ID
100130348
60401
HPRD ID
02230
Ensembl ID
ENSG00000187066
ENSG00000131080
Uniprot IDs
E9PQX1
B2RBZ9
B4DQY6
Q9HAV5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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