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ABI1 and ENAH
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
ABI1
ENAH
Description
abl interactor 1
ENAH actin regulator
Image
No pdb structure
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Nucleus
Endoplasmic Reticulum
Cytosol
Cytoskeleton
Postsynaptic Density
Lamellipodium
Growth Cone
SCAR Complex
Filopodium Tip
Extracellular Exosome
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Lamellipodium
Cell Junction
Filopodium
Synapse
Molecular Function
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Protein Tyrosine Kinase Activator Activity
Signaling Adaptor Activity
Cadherin Binding
Actin Binding
Protein Binding
Profilin Binding
SH3 Domain Binding
WW Domain Binding
Biological Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Polymerization Or Depolymerization
Negative Regulation Of Cell Population Proliferation
Viral Process
Peptidyl-tyrosine Phosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Tyrosine Kinase Activity
Axon Guidance
Actin Polymerization Or Depolymerization
Actin Polymerization-dependent Cell Motility
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Generation of second messenger molecules
Signaling by ROBO receptors
Signaling by ROBO receptors
Drugs
Diseases
GWAS
Delirium (
29631748
)
Depression in smokers (
30219690
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Neuroticism (
27067015
)
Obesity-related traits (
23251661
)
Interacting Genes
64 interacting genes:
ABI2
ABL1
APBB1
C22orf15
CACNA1A
CCDC57
CCHCR1
CYFIP2
DST
DTNB
EIF3H
ENAH
ENKD1
EPS8
EPS8L1
EVL
FAM124B
FBXL19
FHL2
GAS7
HHEX
HNRNPK
HOMER1
HOMER3
HSPA8
KIAA0408
KIAA1217
KTN1
LMO1
MAB21L2
MINK1
MRFAP1
MRFAP1L1
NCK1
NCK2
NCKAP1
NEB
NFASC
NHSL2
NIN
PAK2
PCM1
PRKAA2
PRPF40A
RBM15
RCOR3
SMARCD1
SORBS1
SORBS2
SOS1
SOS2
SPTA1
SPTAN1
SRP68
SRRM1
SYNE2
TCERG1
TLN1
TRIP10
TTC23
VARS2
VASP
WASF1
WASF2
27 interacting genes:
ABI1
ABI2
ABI3
ABL1
APBB1
BAIAP2
DNMBP
EVL
FAT1
FYB1
GPHN
HMGB1
KLHDC3
MAPK1
PFN1
PRPF40A
RAC1
RAD51
ROBO4
SPTA1
TERF2IP
TES
VASP
WAS
XIRP1
YAP1
ZYX
Entrez ID
10006
55740
HPRD ID
04336
12360
Ensembl ID
ENSG00000136754
ENSG00000154380
Uniprot IDs
A0A0A0MRT6
B6VEX3
B6VEX4
B6VEX5
Q8IZP0
A0A4D6J698
Q8N8S7
PDB IDs
2HO2
2IYB
2XQN
4MY6
5N91
5N9C
5N9P
5NAJ
5NBF
5NBX
5NC2
5NC7
5NCF
5NCG
5NCP
5ND0
5NDU
5NEG
6RCF
6RCJ
6RD2
6XVT
6XXR
7A5M
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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